Gil Blander

What Gil talked about

Gil Blander discussed how to think about longevity in terms of healthspan, the number of years lived in good health, rather than just total lifespan. He argued that blood-biomarker-based measures of biological age are more useful than epigenetic clocks because they point to specific, actionable levers rather than just a number. He also described how his views on caloric restriction have shifted over time: while animal studies show strong life-extension effects, he now sees the human evidence as weaker and is less convinced it's a priority intervention.

He worked through what he sees as the most reliable tools currently available for improving healthspan, including consistent sleep, a mix of strength and endurance exercise, regular movement throughout the day, social connection, and reducing alcohol intake. He also spoke about starting a company in this space and framed entrepreneurship as a matter of taking on risk that others are unwilling to take.

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The show

The Total Entrepreneur is a weekly conversation with founders, researchers, and health experts about what actually moves entrepreneurial performance across mind, body, spirit, and business.