Dr. Kara Fitzgerald

What Dr. talked about

Dr. Kara Fitzgerald discussed her randomized controlled trial in which men reduced their biological age by more than three years within eight weeks using a diet and lifestyle intervention, measured through DNA methylation clocks. She explained methylation as an epigenetic mechanism that governs gene expression and responds continuously to diet, sleep, stress, and environmental exposures, and argued that genetics accounts for only about 10% of healthspan and lifespan, leaving most outcomes within an individual's control.

She described follow-up analysis of her research pointing to polyphenol-rich foods, including curcumin, green tea, and berries, as the components doing the most work in reversing biological age within the context of a broader clean diet. She also discussed stress as, in her view, one of the most potent accelerants of aging, and addressed sleep as another factor influencing methylation patterns.

The show

The Total Entrepreneur is a weekly conversation with founders, researchers, and health experts about what actually moves entrepreneurial performance across mind, body, spirit, and business.